The incidence and complications of methicillin-resistant Staphylococcus aureus in a community Level I trauma center.
نویسندگان
چکیده
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) is a growing cause of infections among hospitalized trauma patients. We examined the incidence and infectious consequences of MRSA among trauma patients admitted to our Level I Trauma Center during 24 months. METHODS Nasal swab cultures were obtained at admission and on hospital day 5. Patient demographics and infectious complications were recorded and compared. Differences with p values less than 0.05 were considered significant. RESULTS Admission MRSA screening was positive in 71 patients, yielding a carrier prevalence rate of 5.8% (95% CI 4.5-7.1%). No admission characteristic was associated with positive MRSA screening. Twelve patients (1.7%, 95% CI 0.7-2.6%) who were MRSA negative at admission tested positive for MRSA on hospital day 5. The clinical MRSA infection incidence rate was 1.4% (95% CI 0.7-2.0%). The screening test for MRSA at admission demonstrated a sensitivity of 23.5% (95% CI 6.8-49.9%) and specificity of 94.5% (95% CI 93-95.7%) for predicting MRSA infection. MRSA infections were associated with increased lengths of stay: intensive care unit 17.7 versus 5.1 days, p < 0.001, hospital 23.1 versus 8.6 days, p < 0.001. CONCLUSIONS MRSA infections affect a minority of our trauma patients yet prolong length of stay. Admission MRSA screening of trauma patients does not sufficiently identify patients at risk for infectious complications and should not be practiced.
منابع مشابه
Nasal Colonization Rate of Community and Hospital Acquired Methicillin Resistant Staphylococcus Aureus in Hospitalized Children
Background & Aims: Prevalence of community and hospital acquired methicillin-resistant Staphylococcus aureus (MRSA) infection is increasing. The primary reservoir is the anterior nares; and nasal carriage is a risk factor for infection in a variety of populations. Infection due to hospital-acquired colonization is different from community acquired in clinical manifestations and antibiotics susc...
متن کاملBiofilm Formation in Staphylococcus Aureus and its Relation to Phenotypic and Genotypic Criteria
Abstract Background and Objective: Biofilm is a complex microbial community embedded in a self-produced extracellular polymeric matrix. We aimed to study the extent of biofilm formation by S. Areas isolates and its relation to some phenotypic and genotypic criteria. Material and Methods: One hundred-fifty strains of Staphylococcus aureus isolated from Gorgan were studied. Microtiter plate a...
متن کاملIsolation of PVL/ACME-Positive, Community Acquired, Methicillin-Resistant Staphylococcus aureus (USA300) from Iran
Introduction: Methicillin-Resistant Staphylococcus aureus (MRSA) is responsible for an increasing number of serious hospital- and community-acquired infections. USA300 is known to be the most common cause of community-acquired infections, but recently there have been some reports on hospital-acquired infections caused by this strain. Methods: Totally 171 isolates of S. aureus were collected fro...
متن کاملRisk Factors of Nasal Carriage of Methicillin-Resistant Staphylococcus Aureus and its Antibiotic Susceptibility Pattern in Namazi hospital Healthcare Workers in Shiraz, Iran
Background & Aims: Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen worldwide. The aim of this study was to determine the risk factors of nasal carriage of MRSA and its antibiotic susceptibility pattern among healthcare workers at Namazi Hospital (Shiraz-Iran) Methods: In a cross-sectional study from July to November 2006, nasal swabs were taken from 600 stratif...
متن کاملHypericin Extracts Antibacterial Effect of Cultivated Hypericum perforatum Against Staphylococcus aureus Susceptible and Methicillin-Resistant
Staphylococcus aureus are important factors for infections that acquired of hospital and community. Infections caused by methicillin-resistant Staphylococcus aureus mainly of hospital origin, which in many countries is increasing. For this reason, many researchers have tried to find new compounds as a substitute for these antibiotics. Hypericin is the active substance H.perforatum and licone ma...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of trauma
دوره 67 1 شماره
صفحات -
تاریخ انتشار 2009